buying Rapamycin 53123-88-9 Manufacturer CAS NO.53123-88-9

Buying  Rapamycin  53123-88-9 Manufacturer

Rapamycin is a large cyclosepure antibiotic with a similar structure to Plural (FK506), but with very different immunosuppressive mechanisms. FK506 inhibits the proliferation of T lymphocytes from G0 to G1, while RAPA blocks signaling through different cytokine receptors, blocking the process of T lymphocytes and other cells from G1 to S, and compared to FK506, RAPA blocks calcium-dependent and non-calcium-dependent signaling pathways in T lymphocytes and B lymphocytes. Medical researchers at the University of Chicago used commercially available repamycin oral tablets combined with grapefruit juice to treat melanoma, a common malignant tumor disease in Europe and the United States, which greatly improves the anti-cancer effects of other chemotherapy drugs, thus prolonging patient survival. Studies have shown that rapamycin is easily broken down by enzymes when it enters the digestive tract, and grapefruit juice contains a large amount of furan cumran, which inhibits the destructive effect of digestive enzymes on rapamycin, thus improving the bioavailance of rapamycin. It is said that the earliest Dutch doctors have found: grapefruit juice has the effect of improving the oral absorption of mountain ming, now doctors in Europe and the United States to apply it to rapamycin preparations.

Product packaging:

1) 1kg/bag (net weight 1kg, gross weight 1.1kg, packed in aluminum foil bag)

2) 25kg/drum (net weight 25kg, gross weight 28kg; paper drum packaging with two plastic bags inside; drum size: height 510mm, diameter 360mm)

Storing:

Store in a cool and dry airtight container. 
Keep away from humidity and strong light/heat.

delivery:

Usually within 3-5 working days after full payment.

transportation:

EMS, DHL, TNT, UPS, FEDEX, air freight, sea freight

DHL express, FedEx and EMS below 50KG are usually called DDU services;

Sea freight over 500KG; air freight over 50KG;

For high-value products, please choose air freight and DHL express to ensure safety;