Buy High quality of 98.5%min Tacrolimus 109581-93-3 CAS NO.109581-93-3

Buy High quality of 98.5%min Tacrolimus 109581-93-3

Tacrolimus, also known as FK506, is a fermentation product isolated from the genus streptomyces tsukubaensis, whose chemical structure is a 23-yuan large ring of esters. A powerful new immunosuppressant, it completely inhibits the action of T lymphocytes by inhibiting the release of interleukin-2 (L-2), which is 100 times stronger than cyclosporine (CsA). In recent years, as a first-line medicine for liver and kidney transplantation, it has been listed in 14 countries, including Japan and the United States. Clinical experiments show that it has good efficacy in heart, lung, intestine, bone marrow and other transplants. At the same time, FK506 also plays an active role in the treatment of autoimmune diseases such as ad hoc dermatitis (AD), systemic lupus erythematosus (SLE), autoimmune eye disease, etc. Fitness: Liver. heart. The preferred immunosuppressive drug for kidney and bone marrow transplant patients, which is resistant to traditional immunosuppressive programs after transplantation, is also available. Adverse reactions are similar to cyclosporine. Appearance: white crystalline powder, soluble in methanol, ethyl acetate, chloroform. Melting point: 125-129 degrees C moisture: ≤3.0% ratio of α 23 degrees C, chloroform: -75-90 degrees C heavy metals: <10PPM burning residue: ≤.1% total impurities: ≤2% content: ≥% of the packaging: according to customer demand for long-term preservation needs low temperature.

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