Hot sale reliable quality of Rapamycin 53123-88-9 in stock CAS NO.53123-88-9

Hot sale reliable quality of  Rapamycin 53123-88-9  in stock

Rapamycin (also known as "sirolimus") is a secondary metabolite secreted by Streptomyces soil fungus first discovered from the soil of Easter Island in Chile in 1975. Its chemical structure belongs to the "triene" 
"Macrolide" compounds. Due to the low fermentation yield of rapamycin and the complicated extraction process, the product was not developed and marketed by the American Household Chemicals Company until 1999, and then successively marketed in more than a dozen countries in Europe and America. At that time, the US Food and Drug Administration (FDA) approved the indication of rapamycin not as antibiotics but as "immunosuppressive agents." This is because rapamycin has shown strong immunosuppressive effects in clinical trials, and it can replace cyclosporine with a clinical history of more than 30 years. Moreover, compared with cyclosporine, rapamycin oral liquid has a smaller dose (only 2 to 3 mg each time), a stronger anti-rejection effect, and fewer side effects. Therefore, since rapamycin has been on the market, It has quickly become a commonly used oral immunosuppressant for organ transplant recipients all over the world.

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